Across TCGA pan-cancer cohorts, RN7SKP129 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RN7SKP129’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where RN7SKP129 RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SKP129 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
BRCA are the cancer types where RN7SKP129 tumor–normal differential expression is most reproducible.