RN7SKP127

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RN7SKP127 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RN7SKP127’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RN7SKP127 RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SKP127 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

COAD, READ, and PRAD are the cancer types where RN7SKP127 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SKP127 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADFemaleIII,IV−3.138<.00111view →
READAllAll−2.042<.0015view →
PRADAllAll−0.438.0242view →
BLCAFemaleAll−0.128.0242view →
LUSCAllII,III,IV−0.124.0012view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration