Across TCGA pan-cancer cohorts, RN7SKP124 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RN7SKP124’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where RN7SKP124 RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SKP124 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.
THCA, HNSC, and LUSC are the cancer types where RN7SKP124 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SKP124 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.