Across TCGA pan-cancer cohorts, RN7SKP11 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RN7SKP11’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RN7SKP11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SKP11 is over-expressed in tumor.
HNSC, BRCA, and LUAD are the cancer types where RN7SKP11 tumor–normal differential expression is most reproducible.