RMND5A

Across TCGA pan-cancer cohorts, RMND5A mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RMND5A’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where RMND5A mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types RMND5A is over-expressed in tumor, although a few such as LUAD and COAD show the opposite, repressed pattern.

LSCC, LUAD, and COAD are the cancer types where RMND5A tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RMND5A mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	All	All	+0.137	<.001	6	view →
LUAD	Female	II,III,IV	−0.118	.002	4	view →
COAD	Female	All	−0.118	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RMND5A–LSCC

Open the LSCC breakdown →