RMND1

Across TCGA patient cohorts, RMND1 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RMND1-associated genes across cancer lineages are ACC1, JNK2, and MSH2. Each is linked with RMND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RMND1-to-partner and partner-to-RMND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by RMND1-low versus RMND1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMND1→partner) and Y-score (partner→RMND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.363	+3.000	.047	.036	3	1
UCEC	JNK2 →	+0.197	+3.459	.048	.005	3	1
UCEC	MSH2 →	-0.326	-2.973	.004	.035	3	1
UCEC	mTOR →	+0.185	+3.459	.022	.005	3	1
UCEC	Rab11 →	-0.157	-3.459	.030	.005	3	1
UCEC	S6 →	+0.337	+2.321	.012	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

ACC1 by RMND1 expression — UCEC

Explore this box plot interactively →