RMI2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RMI2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,193 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RMI2-associated genes across cancer lineages are BRIP1, ZNF367, and RMI1. Each is linked with RMI2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RMI2-to-partner and partner-to-RMI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RMI2 versus BRIP1 in LSCC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMI2→partner) and Y-score (partner→RMI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCBRIP1 →+1.134+0.662<.001<.00133
OVZNF367 →+1.774+0.740<.001<.00133
LSCCRMI1 →+0.895+0.477<.001<.00133
OVGPR19 →+1.060+0.576.001<.00133
OVPRIM1 →+1.249+0.606<.001.00233
OVMCM5 →+0.933+0.471.004.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,193 associations by consensus.

RMI2 vs BRIP1 — LSCC

Per-sample scatter of RMI2 vs BRIP1 in LSCC (Pearson r = 0.58).

Explore this scatter interactively →

Exploration