RMI1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RMI1 mutation is significantly associated with the RNA expression of many other genes, with 3,677 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RMI1-associated genes across cancer lineages are CRIP1P4, LINC02052, and CAPZA1P1. Each is linked with RMI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RMI1-to-partner and partner-to-RMI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRIP1P4 grouped by RMI1-low versus RMI1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMI1→partner) and Y-score (partner→RMI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCCRIP1P4 →+0.272+4.544<.001.00932
LIHCLINC02052 →+0.315+4.415<.001.00632
LIHCCAPZA1P1 →+0.082+4.378<.001.00632
COADTOMM22 →+0.438+3.236.001.00832
COADTXN2 →+0.403+2.625.002.00532
UCECL3MBTL2 →+0.466+2.534<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,677 associations by consensus.

CRIP1P4 by RMI1 expression — LIHC

Box plot of CRIP1P4 in RMI1-low vs RMI1-high samples in LIHC.

Explore this box plot interactively →

Exploration