RMI1

Across TCGA cell cohorts, RMI1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RMI1-associated genes across cancer lineages are DPPA5, FAM205A, and SPEM3. Each is linked with RMI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RMI1-to-partner and partner-to-RMI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DPPA5 grouped by RMI1-low versus RMI1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMI1→partner) and Y-score (partner→RMI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	DPPA5 →	+0.055	+5.196	<.001	.005	3	1
LARGE_INTESTINE	FAM205A →	+0.031	+4.029	<.001	<.001	3	1
LARGE_INTESTINE	SPEM3 →	+0.013	+3.347	<.001	.005	3	1
LARGE_INTESTINE	HMX3 →	+0.718	+3.531	<.001	.007	2	1
LARGE_INTESTINE	MYO3A →	+0.472	+3.491	.006	.008	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

DPPA5 by RMI1 expression — OVARY

Explore this box plot interactively →