RMDN3

Across TCGA patient cohorts, RMDN3 RNA expression is significantly associated with the mutation status of many other genes, with 12,496 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RMDN3-associated genes across cancer lineages are OBSCN, KIF26B, and ZNF804A. Each is linked with RMDN3 in more than 4 cancer types. Because this analysis shows association rather than direction, both RMDN3-to-partner and partner-to-RMDN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OBSCN grouped by RMDN3-low versus RMDN3-high in LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMDN3→partner) and Y-score (partner→RMDN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	OBSCN →	+1.390	+0.187	.003	.005	3	5
STAD	KIF26B →	+3.087	+0.435	<.001	<.001	3	4
UCEC	ZNF804A →	+1.818	+0.424	<.001	<.001	3	4
COAD	MUC5B →	+1.720	+0.276	<.001	<.001	3	4
COAD	HERC2 →	+3.094	+0.244	<.001	.002	3	4
STAD	RNF213 →	+2.255	+0.311	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,496 associations by consensus.

OBSCN by RMDN3 expression — LUSC

Explore this box plot interactively →