RMDN3

Across TCGA patient cohorts, RMDN3 mutation is significantly associated with the RNA expression of many other genes, with 630 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RMDN3-associated genes across cancer lineages are RNU6-1318P, MIR6853, and MIR548AD. Each is linked with RMDN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RMDN3-to-partner and partner-to-RMDN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1318P grouped by RMDN3-low versus RMDN3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMDN3→partner) and Y-score (partner→RMDN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1318P →	+0.231	+4.588	.007	.008	3	2
BRCA	MIR6853 →	+0.364	+9.057	<.001	.003	3	1
BRCA	MIR548AD →	+0.338	+8.471	<.001	.005	3	1
UCEC	ZNHIT3 →	+0.546	+3.724	<.001	<.001	3	1
UCEC	MIR6133 →	+0.293	+2.719	.002	.002	3	1
UCEC	FRG1HP →	+0.665	+3.606	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 630 associations by consensus.

RNU6-1318P by RMDN3 expression — BLCA

Explore this box plot interactively →