RMDN3

Across TCGA cell cohorts, RMDN3 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RMDN3-associated genes across cancer lineages are VN1R3, FAM240A, and MCHR2. Each is linked with RMDN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RMDN3-to-partner and partner-to-RMDN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R3 grouped by RMDN3-low versus RMDN3-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMDN3→partner) and Y-score (partner→RMDN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	VN1R3 →	+0.026	+5.285	<.001	.003	3	1
STOMACH	FAM240A →	+0.070	+5.285	<.001	.003	3	1
LARGE_INTESTINE	MCHR2 →	+0.021	+3.684	<.001	.006	3	1
LARGE_INTESTINE	ACER1 →	+0.096	+3.823	.001	.006	3	1
LARGE_INTESTINE	OR1C1 →	+0.072	+3.684	<.001	.006	3	1
LARGE_INTESTINE	NME8 →	+0.352	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

VN1R3 by RMDN3 expression — STOMACH

Explore this box plot interactively →