RMC1

Across TCGA pan-cancer cohorts, RMC1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RMC1 data layer compared with 20 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RMC1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RMC1 expression acts as an unfavorable survival marker.

COAD, CCRCC, and GBM are the cancer types where RMC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.906	1.000	.007	108	view →
CCRCC	DFS	Median	III,IV	0.105	0.928	.003	16	view →
GBM	OS	Median	All	0.387	0.634	.021	7	view →
UCEC	DFS	Median	All	0.935	1.000	.020	4	view →
LUAD	OS	Median	All	0.680	0.939	.013	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RMC1–COAD (DFS)

Open the COAD breakdown →