RMC1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RMC1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,977 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible RMC1-associated genes across cancer lineages are ERMN, KLHL6, and ZNF713. Each is linked with RMC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RMC1-to-partner and partner-to-RMC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RMC1 versus ERMN in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMC1→partner) and Y-score (partner→RMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMERMN →+1.546+0.112<.001<.00135
UCECKLHL6 →+1.019+0.146<.001<.00134
LUADZNF713 →-0.458-0.104.001.00734
COADTRBJ2-7 →+1.285+0.215.001<.00134
CCRCCFTH1P22 →+0.741+0.114.002.00534
CCRCCITGAL →+0.560+0.129.001.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,977 associations by consensus.

RMC1 vs ERMN — GBM

Per-sample scatter of RMC1 vs ERMN in GBM (Pearson r = 0.37).

Explore this scatter interactively →

Exploration