RMC1

Across TCGA cell cohorts, RMC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,241 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RMC1-associated GO terms across cancer lineages are Aggrephagy, Peptidyl-lysine acetylation, and Negative regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with RMC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both RMC1-to-partner and partner-to-RMC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aggrephagy grouped by RMC1-low versus RMC1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RMC1→partner) and Y-score (partner→RMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Aggrephagy →	+0.054	+0.455	.002	.003	3	8
LUNG_SCLC	Peptidyl-lysine acetylation →	+0.082	+0.649	<.001	<.001	3	7
LARGE_INTESTINE	Negative regulation of intracellular steroid hormone receptor signaling pathway →	+0.048	+0.436	.001	.004	2	8
LIVER	Cytoskeleton-dependent cytokinesis →	+0.080	+0.914	.003	.004	3	7
SKIN	Lysosome to ER cholesterol transport →	+0.141	+0.610	<.001	<.001	3	7
CNS	Podocyte cell migration →	+0.093	+0.420	.003	.005	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,241 associations by consensus.

Aggrephagy by RMC1 expression — BLOOD_Leukemia

Explore this box plot interactively →