RLN3

Across TCGA pan-cancer cohorts, RLN3 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RLN3 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RLN3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RLN3 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PAAD show a favorable association.

LUAD, COAD, and BRCA are the cancer types where RLN3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.556	0.318	.002	55	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	51	view →
BRCA	DFS	Tertile	IV	0.273	0.668	.003	42	view →
LGG	OS	Tertile	All	0.731	0.849	<.001	41	view →
PAAD	DFS	Quartile	All	0.438	0.238	.010	27	view →
ESCA	OS	Quartile	III,IV	0.677	0.342	.010	26	view →
CESC	OS	Tertile	All	0.697	0.524	.006	24	view →
THCA	DFS	Quartile	II,III,IV	0.718	0.901	.001	22	view →
LIHC	OS	Tertile	II,III,IV	0.960	0.700	.016	17	view →
GBM	OS	Tertile	All	0.206	0.491	<.001	15	view →
LAML	DFS	Quartile	All	0.394	0.818	<.001	14	view →
KIRC	DFS	Quartile	IV	0.353	0.535	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RLN3–LUAD (DFS)

Open the LUAD breakdown →