RLN2

Across TCGA patient cohorts, RLN2 protein abundance is significantly associated with the RNA expression of many other genes, with 104 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RLN2-associated genes across cancer lineages are PLP2, CISD1, and TOB1. Each is linked with RLN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RLN2-to-partner and partner-to-RLN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RLN2 versus PLP2 in LUAD, with a Pearson correlation of -0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RLN2→partner) and Y-score (partner→RLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PLP2 →	-1.277	-0.710	<.001	.006	3	1
LUAD	CISD1 →	-0.543	-0.730	.007	.009	3	1
LUAD	TOB1 →	+1.525	+0.716	<.001	.005	3	1
LUAD	SNX31 →	-0.210	-0.980	.006	.004	3	1
LUAD	RNU6-1163P →	+1.686	+0.750	.004	.008	3	1
LUAD	RNA5SP298 →	+1.304	+0.716	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 104 associations by consensus.

RLN2 vs PLP2 — LUAD

Explore this scatter interactively →