RLN2

Across TCGA cell cohorts, RLN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,718 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible RLN2-associated GO terms across cancer lineages are Negative regulation of protein localization, Neutrophil-mediated killing of fungus, and Microtubule bundle formation. Each is linked with RLN2 in more than 8 cancer types. Because this analysis shows association rather than direction, both RLN2-to-partner and partner-to-RLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization grouped by RLN2-low versus RLN2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RLN2→partner) and Y-score (partner→RLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of protein localization →	+0.063	+1.603	<.001	.004	3	9
BLOOD_Leukemia	Neutrophil-mediated killing of fungus →	-0.577	-0.366	.009	.008	3	7
OESOPHAGUS	Microtubule bundle formation →	-0.043	-0.939	.004	.006	3	7
OESOPHAGUS	Regulation of myoblast fusion →	+0.124	+1.272	.001	<.001	3	7
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.140	+1.313	<.001	<.001	3	7
OVARY	Vesicle coating →	+0.071	+0.880	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,718 associations by consensus.

Negative regulation of protein localization by RLN2 expression — URINARY_TRACT

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