RLIM

Across TCGA pan-cancer cohorts, RLIM RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RLIM’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RLIM RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RLIM is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

COAD, HNSC, and LIHC are the cancer types where RLIM tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RLIM RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	All	+1.013	<.001	10	view →
HNSC	All	III,IV	+0.806	<.001	10	view →
LIHC	All	II,III,IV	+0.762	<.001	8	view →
STAD	All	II,III,IV	+0.867	<.001	7	view →
READ	All	All	+0.765	<.001	7	view →
BRCA	All	II,III,IV	+0.404	<.001	6	view →
KIRC	Male	II,III,IV	−0.359	.005	6	view →
THCA	All	All	−0.340	<.001	6	view →
CHOL	All	All	+1.821	<.001	5	view →
KICH	All	All	−0.601	.001	4	view →
LUAD	All	All	+0.288	.002	4	view →
KIRP	Female	II,III,IV	+0.798	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RLIM–COAD

Open the COAD breakdown →