RITA1

Across TCGA patient cohorts, RITA1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RITA1-associated genes across cancer lineages are Class-switched memory B-cells, Melanocytes, and HSC. Each is linked with RITA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RITA1-to-partner and partner-to-RITA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Class-switched memory B-cells grouped by RITA1-low versus RITA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RITA1→partner) and Y-score (partner→RITA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Class-switched memory B-cells →	-0.058	-3.459	.043	.005	2	1
UCEC	Melanocytes →	-0.011	-3.405	.037	.005	2	1
UCEC	HSC →	+0.138	+3.470	.012	.003	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Class-switched memory B-cells by RITA1 expression — UCEC

Explore this box plot interactively →