RITA1

Across TCGA cell cohorts, RITA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,891 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RITA1-associated GO terms across cancer lineages are rRNA 5'-end processing, Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Metaphase/anaphase transition of mitotic cell cycle. Each is linked with RITA1 in more than 10 cancer types. Because this analysis shows association rather than direction, both RITA1-to-partner and partner-to-RITA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA 5'-end processing grouped by RITA1-low versus RITA1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RITA1→partner) and Y-score (partner→RITA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	rRNA 5'-end processing →	+0.118	+0.647	<.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.118	+0.647	<.001	.002	3	11
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.205	+0.812	<.001	<.001	3	10
BONE	Regulation of centriole-centriole cohesion →	+0.125	+0.492	<.001	.005	3	10
PANCREAS	Pyrimidine nucleoside diphosphate biosynthetic process →	+0.103	+0.522	.001	.001	3	9
LIVER	Regulation of T cell mediated immunity →	-0.092	-0.471	.002	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,891 associations by consensus.

rRNA 5'-end processing by RITA1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →