RIT2

Across TCGA patient cohorts, RIT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,040 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RIT2-associated GO terms across cancer lineages are Nucleoside triphosphate biosynthetic process, Oxidative phosphorylation, and ATP biosynthetic process. Each is linked with RIT2 in more than 13 cancer types. Because this analysis shows association rather than direction, both RIT2-to-partner and partner-to-RIT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate biosynthetic process grouped by RIT2-low versus RIT2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIT2→partner) and Y-score (partner→RIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleoside triphosphate biosynthetic process →	+0.071	+0.058	<.001	<.001	3	14
STAD	Oxidative phosphorylation →	+0.073	+0.081	<.001	<.001	3	13
STAD	ATP biosynthetic process →	+0.076	+0.058	<.001	<.001	3	13
STAD	Obsolete regulation of histone modification →	+0.065	+0.123	<.001	<.001	3	13
STAD	Mitochondrial electron transport, NADH to ubiquinone →	+0.079	+0.082	<.001	<.001	3	12
STAD	Protein deacetylation →	+0.050	+0.058	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,040 associations by consensus.

Nucleoside triphosphate biosynthetic process by RIT2 expression — STAD

Explore this box plot interactively →