Across TCGA patient cohorts, RIPPLY3 mutation is significantly associated with the RNA expression of many other genes, with 286 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RIPPLY3-associated genes across cancer lineages are RN7SL616P, SNORD116-16, and MIR549A. Each is linked with RIPPLY3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIPPLY3-to-partner and partner-to-RIPPLY3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPPLY3→partner) and Y-score (partner→RIPPLY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL616P →	+0.110	+5.144	<.001	.003	3	2
UCEC	SNORD116-16 →	+1.047	+4.188	<.001	.009	3	2
CESC	MIR549A →	+0.336	+5.342	<.001	.002	3	1
CESC	RNU1-82P →	+0.169	+5.144	<.001	.003	3	1
CESC	RN7SKP263 →	+0.123	+5.569	<.001	.002	3	1
CESC	STAU2P1 →	+0.080	+4.364	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 286 associations by consensus.

Exploration

RIPPLY3 survival (RNA) · tumor vs normal (RNA) · all RIPPLY3 data types