Across TCGA patient cohorts, RIPPLY3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RIPPLY3-associated genes across cancer lineages are mv Endothelial cells and Th2 cells. Each is linked with RIPPLY3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIPPLY3-to-partner and partner-to-RIPPLY3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPPLY3→partner) and Y-score (partner→RIPPLY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	mv Endothelial cells →	-0.028	-3.263	.021	.010	3	1
SKCM	Th2 cells →	+0.253	+1.880	.001	.032	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

RIPPLY3 survival (RNA) · tumor vs normal (RNA) · all RIPPLY3 data types