Across TCGA patient cohorts, RIPPLY2 mutation is significantly associated with the RNA expression of many other genes, with 65 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible RIPPLY2-associated genes across cancer lineages are MIR4530, MIR4725, and RN7SL627P. Each is linked with RIPPLY2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIPPLY2-to-partner and partner-to-RIPPLY2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPPLY2→partner) and Y-score (partner→RIPPLY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4530 →	+0.881	+4.354	.002	.002	3	2
LUSC	MIR4725 →	+0.564	+5.989	<.001	<.001	3	2
UCEC	RN7SL627P →	+0.128	+4.442	<.001	.007	3	1
BLCA	MIR3938 →	+0.273	+7.640	<.001	.009	3	1
BLCA	MIR502 →	+0.312	+7.640	<.001	.009	3	1
BLCA	MIR8069-2 →	+0.313	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

Exploration

RIPPLY2 survival (RNA) · tumor vs normal (RNA) · all RIPPLY2 data types