Across TCGA cell cohorts, RIPPLY2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,222 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RIPPLY2-associated GO terms across cancer lineages are Somite rostral/caudal axis specification, Diencephalon development, and Cytoplasmic translational initiation. Each is linked with RIPPLY2 in more than 8 cancer types. Because this analysis shows association rather than direction, both RIPPLY2-to-partner and partner-to-RIPPLY2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPPLY2→partner) and Y-score (partner→RIPPLY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Somite rostral/caudal axis specification →	+1.180	+2.013	<.001	<.001	3	9
LIVER	Diencephalon development →	-0.117	-1.369	.003	.007	3	5
LUNG_NSCLC_LUAD	Cytoplasmic translational initiation →	+0.041	+0.728	.005	.008	3	5
LIVER	Lipid translocation →	-0.065	-1.976	<.001	.005	3	5
CNS	tRNA splicing, via endonucleolytic cleavage and ligation →	+0.059	+1.293	.001	.001	3	5
LUNG_NSCLC_LUAD	Heart process →	-0.065	-0.883	.008	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,222 associations by consensus.

Exploration

RIPPLY2 survival (RNA) · tumor vs normal (RNA) · all RIPPLY2 data types