RIPOR3

Across TCGA patient cohorts, RIPOR3 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIPOR3-associated genes across cancer lineages are Beclin, S6_pS240_S244, and TFRC. Each is linked with RIPOR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIPOR3-to-partner and partner-to-RIPOR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Beclin grouped by RIPOR3-low versus RIPOR3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPOR3→partner) and Y-score (partner→RIPOR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Beclin →	-0.160	-2.906	.018	.001	3	2
UCEC	S6_pS240_S244 →	+0.301	+1.662	.036	.011	3	2
UCEC	TFRC →	+0.537	+2.584	.004	.010	3	2
UCEC	Caspase-7-cleavedD198 →	+0.615	+2.926	.003	<.001	3	2
UCEC	Cyclin-B1 →	+0.688	+3.584	<.001	.002	3	2
SKCM	eEF2 →	+0.368	+2.906	.008	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Beclin by RIPOR3 expression — SKCM

Explore this box plot interactively →