RIPOR3

Across TCGA cell cohorts, RIPOR3 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RIPOR3-associated genes across cancer lineages are MYOT, NR4A2, and RNF180. Each is linked with RIPOR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIPOR3-to-partner and partner-to-RIPOR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOT grouped by RIPOR3-low versus RIPOR3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPOR3→partner) and Y-score (partner→RIPOR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MYOT →	+0.079	+3.330	.006	<.001	3	1
LARGE_INTESTINE	NR4A2 →	+1.013	+3.082	<.001	.007	3	1
LARGE_INTESTINE	RNF180 →	+0.269	+3.935	.008	<.001	3	1
LARGE_INTESTINE	RXFP1 →	+0.163	+3.791	<.001	.001	3	1
LARGE_INTESTINE	KCTD8 →	+0.187	+2.832	<.001	.002	3	1
CNS	LIM2 →	+0.033	+4.315	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

MYOT by RIPOR3 expression — LARGE_INTESTINE

Explore this box plot interactively →