RIPOR1

Across TCGA pan-cancer cohorts, RIPOR1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated RIPOR1 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RIPOR1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RIPOR1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

LSCC, LUAD, and HNSC are the cancer types where RIPOR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	0.621	0.949	<.001	47	view →
LUAD	DFS	Median	II,III,IV	0.742	0.964	.002	45	view →
HNSC	OS	Quartile	IV	0.894	0.587	.017	19	view →
PDAC	OS	Tertile	IV	0.540	0.934	.038	9	view →
COAD	DFS	Median	IV	0.565	1.000	.028	6	view →
UCEC	DFS	Tertile	All	0.807	0.976	.017	6	view →
CCRCC	DFS	Tertile	All	0.431	0.861	.026	4	view →
GBM	OS	Tertile	All	0.889	0.809	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RIPOR1–LSCC (OS)

Open the LSCC breakdown →