RIPOR1

Across TCGA patient cohorts, RIPOR1 mutation is significantly associated with the RNA expression of many other genes, with 2,861 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIPOR1-associated genes across cancer lineages are RPL23AP45, LINC01943, and KCNJ2-AS1. Each is linked with RIPOR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIPOR1-to-partner and partner-to-RIPOR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP45 grouped by RIPOR1-low versus RIPOR1-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPOR1→partner) and Y-score (partner→RIPOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RPL23AP45 →	+0.097	+5.206	<.001	.007	3	2
UCEC	LINC01943 →	+0.419	+2.616	<.001	<.001	3	2
UCEC	KCNJ2-AS1 →	-0.321	-2.113	.002	.003	3	2
UCEC	TAF5LP1 →	+0.577	+2.654	<.001	<.001	3	2
UCEC	LSP1P1 →	+0.195	+1.628	.003	.008	3	2
COAD	SNU13 →	+0.315	+3.605	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,861 associations by consensus.

RPL23AP45 by RIPOR1 expression — LGG

Explore this box plot interactively →