RIPOR1

Across TCGA patient cohorts, RIPOR1 mutation is significantly associated with the total protein of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIPOR1-associated genes across cancer lineages are PCNA, PKC-b-II_pS660, and ATM. Each is linked with RIPOR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RIPOR1-to-partner and partner-to-RIPOR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by RIPOR1-low versus RIPOR1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPOR1→partner) and Y-score (partner→RIPOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PCNA →	+0.371	+3.330	.001	.005	3	3
COAD	PKC-b-II_pS660 →	-0.480	-3.000	.003	.034	3	3
UCEC	ATM →	-0.531	-3.700	.001	.001	3	3
UCEC	Caspase-7-cleavedD198 →	+0.916	+2.926	<.001	<.001	3	3
UCEC	G6PD →	+0.370	+2.235	.001	.005	3	2
COAD	MEK1 →	+0.210	+2.195	.025	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

PCNA by RIPOR1 expression — COAD

Explore this box plot interactively →