RIPK4

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RIPK4 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIPK4-associated genes across cancer lineages are p62 Lck ligand, Caspase-8, and EGFR_pY1068. Each is linked with RIPK4 in more than 2 cancer types. Because this analysis shows association rather than direction, both RIPK4-to-partner and partner-to-RIPK4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPK4→partner) and Y-score (partner→RIPK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMp62 Lck ligand →+0.445+2.334.012.01832
UCECCaspase-8 →-0.218-1.906.031.01632
UCECEGFR_pY1068 →-0.266-1.906.008.01632
UCECPCNA →+0.176+2.321.043.03332
UCECAMPK_pT172 →+0.371+3.321.024.00932
COADER-alpha_pS118 →+0.164+2.815.008.03631
Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

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