Across TCGA cell cohorts, RIPK4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,578 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RIPK4-associated GO terms across cancer lineages are Negative regulation of actin filament polymerization, Positive regulation of protein import into nucleus, and Skin development. Each is linked with RIPK4 in more than 9 cancer types. Because this analysis shows association rather than direction, both RIPK4-to-partner and partner-to-RIPK4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPK4→partner) and Y-score (partner→RIPK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of actin filament polymerization →	+0.136	+1.366	<.001	<.001	3	10
BREAST	Positive regulation of protein import into nucleus →	+0.099	+1.674	.001	<.001	3	10
BREAST	Skin development →	+0.141	+1.500	<.001	<.001	3	10
BREAST	Type II interferon-mediated signaling pathway →	+0.198	+1.433	<.001	<.001	3	10
LARGE_INTESTINE	Regulation of ruffle assembly →	+0.143	+1.109	<.001	<.001	3	9
OVARY	Plasma membrane organization →	+0.103	+1.996	<.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,578 associations by consensus.

Exploration

RIPK4 survival (RNA) · tumor vs normal (RNA) · all RIPK4 data types