RIPK3

Across TCGA patient cohorts, RIPK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,714 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RIPK3-associated proteins across cancer lineages are RIPK3_S316, RIPK3_S339, and PYCARD. Each is linked with RIPK3 in more than 8 cancer types. Because this analysis shows association rather than direction, both RIPK3-to-partner and partner-to-RIPK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIPK3 versus RIPK3_S316 in HNSC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPK3→partner) and Y-score (partner→RIPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RIPK3_S316 →	+0.572	+1.028	<.001	<.001	3	9
BRCA	RIPK3_S339 →	+0.927	+1.385	<.001	<.001	3	8
GBM	PYCARD →	+0.715	+0.874	<.001	<.001	3	7
GBM	ARHGDIB →	+0.851	+0.893	<.001	<.001	3	6
BRCA	RIPK3_S410 →	+0.736	+1.223	<.001	<.001	3	6
PDAC	SH3BGRL3 →	+0.400	+0.444	.007	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,714 associations by consensus.

RIPK3 vs RIPK3_S316 — HNSC

Explore this scatter interactively →