RIPK1

Across TCGA patient cohorts, RIPK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,025 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RIPK1-associated proteins across cancer lineages are CD5L, TPMT, and ZNF318_S527. Each is linked with RIPK1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RIPK1-to-partner and partner-to-RIPK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIPK1 versus CD5L in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPK1→partner) and Y-score (partner→RIPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CD5L →	+0.798	+0.615	<.001	<.001	3	4
OV	TPMT →	+0.489	+0.529	.002	.001	3	4
GBM	ZNF318_S527 →	+0.372	+0.280	<.001	<.001	3	3
LUAD	MANF →	-0.409	-0.339	.001	.001	3	3
BRCA	EXOC2 →	+0.170	+0.334	<.001	<.001	3	3
UCEC	GATAD2B →	+0.217	+0.408	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,025 associations by consensus.

RIPK1 vs CD5L — OV

Explore this scatter interactively →