RIOX1

Across TCGA patient cohorts, RIOX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,178 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RIOX1-associated proteins across cancer lineages are ZC3H14, MTHFD1, and YLPM1. Each is linked with RIOX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RIOX1-to-partner and partner-to-RIOX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIOX1 versus ZC3H14 in LSCC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RIOX1→partner) and Y-score (partner→RIOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZC3H14 →	+0.230	+0.455	<.001	<.001	3	7
OV	MTHFD1 →	+0.427	+0.525	<.001	<.001	3	7
LSCC	YLPM1 →	+0.255	+0.573	<.001	<.001	3	6
LSCC	UBR7 →	+0.433	+0.540	<.001	<.001	3	5
LSCC	VRK1 →	+0.561	+0.528	<.001	<.001	3	5
BRCA	NEK9 →	+0.218	+0.343	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,178 associations by consensus.

RIOX1 vs ZC3H14 — LSCC

Explore this scatter interactively →