RIOX1

Across TCGA patient cohorts, RIOX1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,583 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RIOX1-associated genes across cancer lineages are MED6, CLBA1, and PPP4R3A. Each is linked with RIOX1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RIOX1-to-partner and partner-to-RIOX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIOX1 versus MED6 in LUAD, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIOX1→partner) and Y-score (partner→RIOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MED6 →	+0.493	+0.276	<.001	<.001	3	6
LSCC	CLBA1 →	+0.704	+0.287	<.001	<.001	3	5
COAD	PPP4R3A →	+0.480	+0.280	.002	<.001	3	5
COAD	EIF2S1 →	+0.500	+0.329	.003	<.001	3	5
OV	PSEN1 →	+0.406	+0.390	<.001	<.001	3	5
OV	POMT2 →	+0.456	+0.224	.003	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,583 associations by consensus.

RIOX1 vs MED6 — LUAD

Explore this scatter interactively →