RIOX1

Across TCGA cell cohorts, RIOX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,908 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RIOX1-associated GO terms across cancer lineages are Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Nuclear histone mRNA catabolic process, and Regulation of DNA-templated DNA replication. Each is linked with RIOX1 in more than 11 cancer types. Because this analysis shows association rather than direction, both RIOX1-to-partner and partner-to-RIOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by RIOX1-low versus RIOX1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIOX1→partner) and Y-score (partner→RIOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.099	+1.096	<.001	<.001	3	12
STOMACH	Nuclear histone mRNA catabolic process →	+0.127	+1.150	<.001	.002	3	12
OESOPHAGUS	Regulation of DNA-templated DNA replication →	+0.132	+0.718	<.001	<.001	3	12
OVARY	rRNA 5'-end processing →	+0.130	+0.942	<.001	.005	3	11
SKIN	Protein farnesylation →	+0.196	+0.715	<.001	<.001	3	11
OVARY	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.130	+0.942	<.001	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,908 associations by consensus.

Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by RIOX1 expression — OVARY

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