RIOK2

Across TCGA patient cohorts, RIOK2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,985 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible RIOK2-associated genes across cancer lineages are OASL, CXCR2P1, and SNX10. Each is linked with RIOK2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RIOK2-to-partner and partner-to-RIOK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIOK2 versus OASL in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIOK2→partner) and Y-score (partner→RIOK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OASL →	+1.662	+0.267	<.001	<.001	3	4
HNSC	CXCR2P1 →	+1.148	+0.299	.003	<.001	3	4
COAD	SNX10 →	+1.078	+0.648	.005	.006	3	4
UCEC	RBMS3 →	-0.536	-0.214	.002	.001	3	4
CCRCC	SOS2 →	-0.484	-0.409	<.001	<.001	3	4
GBM	SEPTIN4 →	-1.098	-0.354	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,985 associations by consensus.

RIOK2 vs OASL — HNSC

Explore this scatter interactively →