RIOK2

Across TCGA cell cohorts, RIOK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,111 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RIOK2-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Regulation of ribonucleoprotein complex localization, and Regulation of rRNA processing. Each is linked with RIOK2 in more than 16 cancer types. Because this analysis shows association rather than direction, both RIOK2-to-partner and partner-to-RIOK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by RIOK2-low versus RIOK2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIOK2→partner) and Y-score (partner→RIOK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of rRNA processing →	+0.197	+0.947	<.001	<.001	3	17
URINARY_TRACT	Regulation of ribonucleoprotein complex localization →	+0.128	+0.715	<.001	<.001	3	16
OESOPHAGUS	Regulation of rRNA processing →	+0.161	+0.822	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Dihydrofolate metabolic process →	+0.201	+0.839	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Interkinetic nuclear migration →	+0.123	+0.928	<.001	<.001	3	10
LARGE_INTESTINE	Nucleotide-excision repair →	+0.058	+0.687	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,111 associations by consensus.

Positive regulation of rRNA processing by RIOK2 expression — OESOPHAGUS

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