RIOK2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RIOK2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RIOK2-associated genes across cancer lineages are C10orf53. Each is linked with RIOK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIOK2-to-partner and partner-to-RIOK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf53 grouped by RIOK2-low versus RIOK2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIOK2→partner) and Y-score (partner→RIOK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEC10orf53 →+0.012+3.632<.001.00331
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

C10orf53 by RIOK2 expression — LARGE_INTESTINE

Box plot of C10orf53 in RIOK2-low vs RIOK2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration