RIOK1

Across TCGA patient cohorts, RIOK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,543 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RIOK1-associated proteins across cancer lineages are WRNIP1, NUP153, and XPO5. Each is linked with RIOK1 in more than 8 cancer types. Because this analysis shows association rather than direction, both RIOK1-to-partner and partner-to-RIOK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIOK1 versus WRNIP1 in OV, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RIOK1→partner) and Y-score (partner→RIOK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WRNIP1 →	+0.548	+0.541	<.001	<.001	3	9
LSCC	NUP153 →	+0.349	+0.721	<.001	<.001	3	9
LSCC	XPO5 →	+0.743	+0.754	<.001	<.001	3	8
LSCC	CDYL →	+0.425	+0.833	<.001	<.001	3	8
OV	DHX16 →	+0.291	+0.780	<.001	<.001	3	8
LSCC	MCM3 →	+0.756	+0.683	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,543 associations by consensus.

RIOK1 vs WRNIP1 — OV

Explore this scatter interactively →