RIOK1

Across TCGA patient cohorts, RIOK1 mutation is significantly associated with the RNA expression of many other genes, with 2,085 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIOK1-associated genes across cancer lineages are RNU6-1292P, RNU1-17P, and TRAJ28. Each is linked with RIOK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RIOK1-to-partner and partner-to-RIOK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1292P grouped by RIOK1-low versus RIOK1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIOK1→partner) and Y-score (partner→RIOK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1292P →	+0.238	+3.038	<.001	.006	3	3
CESC	RNU1-17P →	+0.395	+5.103	<.001	.008	3	3
COAD	TRAJ28 →	+1.491	+4.324	<.001	.007	3	2
UCEC	LINC01151 →	+0.423	+2.618	.006	<.001	3	2
CESC	UBE2V1P4 →	+0.127	+5.103	<.001	.008	3	1
CESC	VN2R9P →	+0.038	+5.201	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,085 associations by consensus.

RNU6-1292P by RIOK1 expression — UCEC

Explore this box plot interactively →