RINT1

Across TCGA pan-cancer cohorts, RINT1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RINT1 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RINT1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RINT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, UCEC, and LUAD are the cancer types where RINT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	IV	0.843	0.619	.024	12	view →
UCEC	DFS	Median	All	0.953	0.859	.041	6	view →
LUAD	OS	Quartile	II,III,IV	1.000	0.793	.032	4	view →
CCRCC	DFS	Median	All	0.967	0.865	.041	3	view →
GBM	DFS	Median	All	0.752	0.688	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RINT1–HNSC (OS)

Open the HNSC breakdown →