RINT1

Across TCGA patient cohorts, RINT1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,265 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RINT1-associated genes across cancer lineages are ASXL1, TMEM43, and CTDSP2. Each is linked with RINT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RINT1-to-partner and partner-to-RINT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RINT1 versus ASXL1 in COAD, with a Pearson correlation of -0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RINT1→partner) and Y-score (partner→RINT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASXL1 →	-0.564	-0.191	<.001	.006	3	5
UCEC	TMEM43 →	-0.453	-0.141	.006	.007	3	4
UCEC	CTDSP2 →	-0.688	-0.174	<.001	<.001	3	4
LSCC	FGD6 →	-0.440	-0.131	.005	<.001	3	4
PDAC	GCC1 →	+0.297	+0.172	<.001	<.001	3	4
COAD	CEP68 →	-0.473	-0.226	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,265 associations by consensus.

RINT1 vs ASXL1 — COAD

Explore this scatter interactively →