RINT1

Across TCGA patient cohorts, RINT1 mutation is significantly associated with the RNA expression of many other genes, with 1,291 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RINT1-associated genes across cancer lineages are RN7SL627P, MIR8053, and ZSWIM5P1. Each is linked with RINT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RINT1-to-partner and partner-to-RINT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL627P grouped by RINT1-low versus RINT1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RINT1→partner) and Y-score (partner→RINT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL627P →	+0.096	+4.618	.002	.005	3	3
SKCM	MIR8053 →	+0.266	+4.328	<.001	.007	3	3
BLCA	ZSWIM5P1 →	+0.012	+4.147	<.001	.009	3	2
BLCA	TRIM51EP →	+0.077	+4.106	<.001	.002	3	2
BLCA	WRBP1 →	+0.153	+3.317	.002	.008	3	2
HNSC	RN7SKP120 →	+0.056	+5.626	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,291 associations by consensus.

RN7SL627P by RINT1 expression — BLCA

Explore this box plot interactively →