RINT1

Across TCGA cell cohorts, RINT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,427 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RINT1-associated GO terms across cancer lineages are Microtubule organizing center organization, Centrosome cycle, and Positive regulation of isotype switching to IgG isotypes. Each is linked with RINT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both RINT1-to-partner and partner-to-RINT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by RINT1-low versus RINT1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RINT1→partner) and Y-score (partner→RINT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.067	+0.711	.005	.001	3	14
BLOOD_Leukemia	Centrosome cycle →	+0.067	+0.559	<.001	<.001	3	13
PANCREAS	Positive regulation of isotype switching to IgG isotypes →	+0.152	+0.709	<.001	<.001	3	13
BLOOD_Lymphoma	Meiotic cell cycle →	+0.058	+0.644	<.001	.005	3	11
BLOOD_Lymphoma	Positive regulation of rRNA processing →	+0.161	+0.935	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	tRNA dihydrouridine synthesis →	+0.099	+0.729	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,427 associations by consensus.

Microtubule organizing center organization by RINT1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →