Across TCGA patient cohorts, RINL mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RINL-associated genes across cancer lineages are FoxM1, Cyclin-B1, and eIF4G. Each is linked with RINL in more than 1 cancer types. Because this analysis shows association rather than direction, both RINL-to-partner and partner-to-RINL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RINL→partner) and Y-score (partner→RINL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.284	+2.906	.009	.001	3	2
UCEC	Cyclin-B1 →	+0.594	+2.321	.012	.033	3	2
UCEC	eIF4G →	+0.383	+3.321	.003	.009	3	1
UCEC	G6PD →	-0.285	-2.222	.037	.011	3	1
UCEC	JNK2 →	+0.290	+2.222	<.001	.011	3	1
UCEC	Ku80 →	+0.304	+3.472	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

RINL survival (RNA) · tumor vs normal (RNA) · all RINL data types