Across TCGA patient cohorts, RING1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,229 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RING1-associated genes across cancer lineages are ZKSCAN4, ZSCAN26, and EIF3J-DT. Each is linked with RING1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RING1-to-partner and partner-to-RING1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RING1→partner) and Y-score (partner→RING1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZKSCAN4 →	+0.515	+0.271	<.001	<.001	3	7
HNSC	ZSCAN26 →	+0.597	+0.277	.002	<.001	3	7
CCRCC	EIF3J-DT →	+0.450	+0.189	<.001	.005	3	6
OV	ZNF563 →	+0.799	+0.253	<.001	.002	3	6
HNSC	C14orf93 →	+0.508	+0.270	.001	<.001	3	6
HNSC	POGZ →	+0.497	+0.230	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,229 associations by consensus.

Exploration

RING1 survival (RNA) · tumor vs normal (RNA) · all RING1 data types