RING1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RING1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RING1-associated genes across cancer lineages are INPP4B and JNK2. Each is linked with RING1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RING1-to-partner and partner-to-RING1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RING1→partner) and Y-score (partner→RING1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECINPP4B →-0.322-2.571.032.01131
UCECJNK2 →+0.195+2.834.035.03431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration